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The oral GLP-1 receptor agonist semaglutide (Rybelsus) did not slow Alzheimer's disease progression in the highly awaited EVOKE phase III trials, Novo Nordisk announced Monday. Read more at: https://www.medpagetoday.com/neurology/alzheimersdisease
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A 2024 Alzheimer's & Dementia study of 1,094,761 type-2 diabetics showed semaglutide cut first-time Alzheimer's diagnoses by ~70% versus conventional antidiabetics. (Wang et al.) We used to talk about GLP-1 agonism as
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Semaglutide attenuates Alzheimer's disease model progression by targeting microglial NLRP3 inflammasome-mediated neuroinflammation and ferroptosis
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